Detalhe da pesquisa
1.
Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice.
Hepatology
; 71(1): 247-258, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31136002
2.
Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice.
J Hepatol
; 71(1): 153-162, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30935993
3.
Pivotal role of glutamine synthetase in ammonia detoxification.
Hepatology
; 65(1): 281-293, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27641632
4.
The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator.
Biochim Biophys Acta
; 1863(9): 2280-8, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27301931
5.
ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes.
Hepatology
; 64(1): 161-74, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26926206
6.
Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.
Hepatology
; 62(1): 207-19, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641256
7.
FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model.
Biochim Biophys Acta
; 1842(5): 739-46, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24548803
8.
ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.
Arterioscler Thromb Vasc Biol
; 34(9): 1985-9, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24969777
9.
ATP8B1 and ATP11C: Two Lipid Flippases Important for Hepatocyte Function.
Dig Dis
; 33(3): 314-8, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26045263
10.
Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis.
Lab Invest
; 94(10): 1103-13, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25068656
11.
Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity.
Hepatology
; 57(4): 1509-17, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23184615
12.
The phospholipid flippase ATP8B1 is involved in the pathogenesis of Ulcerative Colitis via establishment of intestinal barrier function.
J Crohns Colitis
; 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366839
13.
Overexpression of insulin like growth factor binding protein 5 reduces liver fibrosis in chronic cholangiopathy.
Biochim Biophys Acta
; 1822(6): 996-1003, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22434064
14.
Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.
Biochim Biophys Acta
; 1822(8): 1223-9, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22546842
15.
Oral availability of cefadroxil depends on ABCC3 and ABCC4.
Drug Metab Dispos
; 40(3): 515-21, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22166395
16.
Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice.
JHEP Rep
; 4(11): 100573, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36160754
17.
Low efficacy of recombinant SV40 in Ugt1a1-/- mice with severe inherited hyperbilirubinemia.
PLoS One
; 16(4): e0250605, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891666
18.
Reduced spontaneous itch in mouse models of cholestasis.
Sci Rep
; 11(1): 6127, 2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731871
19.
Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients.
Mol Ther Methods Clin Dev
; 20: 287-297, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33511243
20.
Soluble adenylyl cyclase regulates the cytosolic NADH/NAD+ redox state and the bioenergetic switch between glycolysis and oxidative phosphorylation.
Biochim Biophys Acta Bioenerg
; 1862(4): 148367, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33412125